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FLT3 Inhibition and Mechanisms of Drug Resistance in mutant FLT3-Positive AML

An appealing therapeutic target for AML is constitutively-activated, mutant FLT3, which is expressed in a subpopulation of AML patients and is generally a poor prognostic indicator in patients under the age of 65. There are currently several FLT3 inhibitors that are undergoing clinical investigation...

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Bibliografische gegevens
Gepubliceerd in:Drug Resist Updat
Hoofdauteurs: Weisberg, Ellen, Barrett, Rosemary, Liu, Qingsong, Stone, Richard, Gray, Nathanael, Griffin, James D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472331/
https://ncbi.nlm.nih.gov/pubmed/19467916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2009.04.001
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