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FLT3 Inhibition and Mechanisms of Drug Resistance in mutant FLT3-Positive AML
An appealing therapeutic target for AML is constitutively-activated, mutant FLT3, which is expressed in a subpopulation of AML patients and is generally a poor prognostic indicator in patients under the age of 65. There are currently several FLT3 inhibitors that are undergoing clinical investigation...
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| Publicado no: | Drug Resist Updat |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4472331/ https://ncbi.nlm.nih.gov/pubmed/19467916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2009.04.001 |
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