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Ikaros mediates gene silencing in T cells through Polycomb repressive complex 2
T-cell development is accompanied by epigenetic changes that ensure the silencing of stem cell-related genes and the activation of lymphocyte-specific programmes. How transcription factors influence these changes remains unclear. We show that the Ikaros transcription factor forms a complex with Poly...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4667618/ https://ncbi.nlm.nih.gov/pubmed/26549758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9823 |
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