Sumoylation Inhibits the Growth Suppressive Properties of Ikaros

The Ikaros transcription factor is a tumor suppressor that is also important for lymphocyte development. How post-translational modifications influence Ikaros function remains partially understood. We show that Ikaros undergoes sumoylation in developing T cells that correspond to mono-, bi- or poly-...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Apostolov, Apostol, Litim-Mecheri, Isma, Oravecz, Attila, Goepp, Marie, Kirstetter, Peggy, Marchal, Patricia, Ittel, Antoine, Mauvieux, Laurent, Chan, Susan, Kastner, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912065/
https://ncbi.nlm.nih.gov/pubmed/27315244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157767
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