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Ikaros mediates gene silencing in T cells through Polycomb repressive complex 2

T-cell development is accompanied by epigenetic changes that ensure the silencing of stem cell-related genes and the activation of lymphocyte-specific programmes. How transcription factors influence these changes remains unclear. We show that the Ikaros transcription factor forms a complex with Poly...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Oravecz, Attila, Apostolov, Apostol, Polak, Katarzyna, Jost, Bernard, Le Gras, Stéphanie, Chan, Susan, Kastner, Philippe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Pub. Group 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667618/
https://ncbi.nlm.nih.gov/pubmed/26549758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9823
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