Transfection of microRNA Mimics Should Be Used with Caution

Transient transfection of chemically synthesized microRNA (miRNA) mimics is being used extensively to study the functions and mechanisms of endogenous miRNAs. However, it remains unclear whether transfected miRNAs behave similarly to endogenous miRNAs. Here we show that transient transfection of miR...

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Detalles Bibliográficos
Publicado en:Front Genet
Main Authors: Jin, Hyun Yong, Gonzalez-Martin, Alicia, Miletic, Ana V., Lai, Maoyi, Knight, Sarah, Sabouri-Ghomi, Mohsen, Head, Steven R., Macauley, Matthew S., Rickert, Robert C., Xiao, Changchun
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2015
Assuntos:
Genetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667072/
https://ncbi.nlm.nih.gov/pubmed/26697058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00340
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