MicroRNA-17∼92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways

MicroRNAs (miRNAs) have been broadly implicated in cancer, but their exact function and mechanism in carcinogenesis remain poorly understood. Elevated miR-17∼92 expression is frequently found in human cancers, mainly due to gene amplification and Myc-mediated transcriptional upregulation. Here we sh...

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Hauptverfasser: Jin, Hyun Yong, Oda, Hiroyo, Lai, Maoyi, Skalsky, Rebecca L, Bethel, Kelly, Shepherd, Jovan, Kang, Seung Goo, Liu, Wen-Hsien, Sabouri-Ghomi, Mohsen, Cullen, Bryan R, Rajewsky, Klaus, Xiao, Changchun
Format: Artigo
Sprache:Inglês
Veröffentlicht: European Molecular Biology Organization 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771343/
https://ncbi.nlm.nih.gov/pubmed/23921550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.178
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