Transfection of microRNA Mimics Should Be Used with Caution

Transient transfection of chemically synthesized microRNA (miRNA) mimics is being used extensively to study the functions and mechanisms of endogenous miRNAs. However, it remains unclear whether transfected miRNAs behave similarly to endogenous miRNAs. Here we show that transient transfection of miR...

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Bibliografske podrobnosti
izdano v:Front Genet
Main Authors: Jin, Hyun Yong, Gonzalez-Martin, Alicia, Miletic, Ana V., Lai, Maoyi, Knight, Sarah, Sabouri-Ghomi, Mohsen, Head, Steven R., Macauley, Matthew S., Rickert, Robert C., Xiao, Changchun
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Genetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667072/
https://ncbi.nlm.nih.gov/pubmed/26697058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00340
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