Transfection of microRNA Mimics Should Be Used with Caution

Transient transfection of chemically synthesized microRNA (miRNA) mimics is being used extensively to study the functions and mechanisms of endogenous miRNAs. However, it remains unclear whether transfected miRNAs behave similarly to endogenous miRNAs. Here we show that transient transfection of miR...

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Bibliographische Detailangaben
Veröffentlicht in:Front Genet
Hauptverfasser: Jin, Hyun Yong, Gonzalez-Martin, Alicia, Miletic, Ana V., Lai, Maoyi, Knight, Sarah, Sabouri-Ghomi, Mohsen, Head, Steven R., Macauley, Matthew S., Rickert, Robert C., Xiao, Changchun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667072/
https://ncbi.nlm.nih.gov/pubmed/26697058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00340
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