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MicroRNA-Target Binding Structures Mimic MicroRNA Duplex Structures in Humans

Traditionally, researchers match a microRNA guide strand to mRNA sequences using sequence comparisons to predict its potential target genes. However, many of the predictions can be false positives due to limitations in sequence comparison alone. In this work, we consider the association of two relat...

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Detalhes bibliográficos
Main Authors: Chen, Xi, Shen, Lu, Chou, Hui-Hsien
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923817/
https://ncbi.nlm.nih.gov/pubmed/24551166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088806
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