Alternative RISC assembly: Binding and repression of microRNA–mRNA duplexes by human Ago proteins

MicroRNAs (miRNAs) are small noncoding RNAs that post-transcriptionally regulate protein output from the majority of human mRNAs. In contrast to the consensus view that all miRNAs are associated with Argonaute (Ago) proteins, we determine that miRNAs are expressed in a 13-fold excess relative to Ago...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Janas, Maja M., Wang, Bingbing, Harris, Abigail S., Aguiar, Mike, Shaffer, Jonathan M., Subrahmanyam, Yerramilli V.B.K., Behlke, Mark A., Wucherpfennig, Kai W., Gygi, Steven P., Gagnon, Etienne, Novina, Carl D.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479394/
https://ncbi.nlm.nih.gov/pubmed/23019594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.035675.112
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares