The Influence of the 1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole-4-yl Moiety on the Adenosine Receptors Affinity Profile of Pyrazolo[4,3-e][1,2,4]Triazolo[1,5-c]Pyrimidine Derivatives

A new series of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine (PTP) derivatives has been developed in order to explore their affinity and selectivity profile at the four adenosine receptor subtypes. In particular, the PTP scaffold was conjugated at the C2 position with the 1-(3-trifluoromethyl-ben...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Federico, Stephanie, Redenti, Sara, Sturlese, Mattia, Ciancetta, Antonella, Kachler, Sonja, Klotz, Karl-Norbert, Cacciari, Barbara, Moro, Stefano, Spalluto, Giampiero
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666649/
https://ncbi.nlm.nih.gov/pubmed/26625265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143504
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares