Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines to develop functionalized ligands to target adenosine receptors: fluorescent ligands as an example

A series of adenosine receptor antagonists bearing a reactive linker was developed. Functionalization of these derivatives is useful to easily obtain multi-target ligands, receptor probes, drug delivery systems, and diagnostic or theranostic systems. The pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidi...

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Publicado en:Medchemcomm
Autores principales: Federico, Stephanie, Margiotta, Enrico, Paoletta, Silvia, Kachler, Sonja, Klotz, Karl-Norbert, Jacobson, Kenneth A., Pastorin, Giorgia, Moro, Stefano, Spalluto, Giampiero
Formato: Artigo
Lenguaje:Inglês
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6644567/
https://ncbi.nlm.nih.gov/pubmed/31391881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00014c
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