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Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: Effect of the N-5 bond type on the affinity and selectivity at the four adenosine receptor subtypes

In the last few years, many efforts have been made to search for potent and selective human A(3) adenosine antagonists. In particular, one of the most promising human A(3) adenosine receptor antagonists is represented by the pyrazolo-triazolo-pyrimidine family. This class of compounds has been stron...

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Detalhes bibliográficos
Main Authors: Bolcato, Chiara, Cusan, Claudia, Pastorin, Giorgia, Spalluto, Giampiero, Cacciari, Barbara, Klotz, Karl Norbert, Morizzo, Erika, Moro, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2245997/
https://ncbi.nlm.nih.gov/pubmed/18368532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-007-9058-y
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