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Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: Effect of the N-5 bond type on the affinity and selectivity at the four adenosine receptor subtypes

In the last few years, many efforts have been made to search for potent and selective human A(3) adenosine antagonists. In particular, one of the most promising human A(3) adenosine receptor antagonists is represented by the pyrazolo-triazolo-pyrimidine family. This class of compounds has been stron...

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Autors principals: Bolcato, Chiara, Cusan, Claudia, Pastorin, Giorgia, Spalluto, Giampiero, Cacciari, Barbara, Klotz, Karl Norbert, Morizzo, Erika, Moro, Stefano
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2245997/
https://ncbi.nlm.nih.gov/pubmed/18368532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-007-9058-y
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