Characterisation of aptamer–target interactions by branched selection and high-throughput sequencing of SELEX pools

Nucleic acid aptamer selection by systematic evolution of ligands by exponential enrichment (SELEX) has shown great promise for use in the development of research tools, therapeutics and diagnostics. Typically, aptamers are identified from libraries containing up to 10(16) different RNA or DNA seque...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Dupont, Daniel M., Larsen, Niels, Jensen, Jan. K., Andreasen, Peter A., Kjems, Jørgen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
Methods Online
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666376/
https://ncbi.nlm.nih.gov/pubmed/26163061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv700
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