Characterisation of aptamer–target interactions by branched selection and high-throughput sequencing of SELEX pools

Nucleic acid aptamer selection by systematic evolution of ligands by exponential enrichment (SELEX) has shown great promise for use in the development of research tools, therapeutics and diagnostics. Typically, aptamers are identified from libraries containing up to 10(16) different RNA or DNA seque...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Dupont, Daniel M., Larsen, Niels, Jensen, Jan. K., Andreasen, Peter A., Kjems, Jørgen
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
Предметы:
Methods Online
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666376/
https://ncbi.nlm.nih.gov/pubmed/26163061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv700
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