Selection of DNA aptamers for ovarian cancer biomarker HE4 using CE-SELEX and high-throughput sequencing

The development of novel affinity probes for cancer biomarkers may enable powerful improvements in analytical methods for detecting and treating cancer. In this report, we describe our use of capillary electrophoresis (CE) as the separation mechanism in the process of selecting DNA aptamers with aff...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Anal Bioanal Chem
Prif Awduron: Eaton, Rachel M., Shallcross, Jamie A., Mael, Liora E., Mears, Kepler S., Minkoff, Lisa, Scoville, Delia J., Whelan, Rebecca J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551533/
https://ncbi.nlm.nih.gov/pubmed/25863801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-015-8665-7
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