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Selection of DNA aptamers for ovarian cancer biomarker HE4 using CE-SELEX and high-throughput sequencing

The development of novel affinity probes for cancer biomarkers may enable powerful improvements in analytical methods for detecting and treating cancer. In this report, we describe our use of capillary electrophoresis (CE) as the separation mechanism in the process of selecting DNA aptamers with aff...

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Detalhes bibliográficos
Publicado no:Anal Bioanal Chem
Main Authors: Eaton, Rachel M., Shallcross, Jamie A., Mael, Liora E., Mears, Kepler S., Minkoff, Lisa, Scoville, Delia J., Whelan, Rebecca J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551533/
https://ncbi.nlm.nih.gov/pubmed/25863801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-015-8665-7
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