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Tracking the Emergence of High Affinity Aptamers for rhVEGF(165) During CE-SELEX Using High Throughput Sequencing
CE-SELEX is a powerful technique for isolating aptamers for various targets, from large proteins to small peptides with molecular weights of several kilodaltons. One of the unique characteristics of CE-SELEX is the relatively high heterogeneity of the ssDNA pools that remains even after multiple rou...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3892959/ https://ncbi.nlm.nih.gov/pubmed/24125636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac401875h |
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