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Post-ExSELEX stabilization of an unnatural-base DNA aptamer targeting VEGF(165) toward pharmaceutical applications
A new technology, genetic alphabet expansion using artificial bases (unnatural bases), has created high-affinity DNA ligands (aptamers) that specifically bind to target proteins by ExSELEX (genetic alphabet Expansion for Systematic Evolution of Ligands by EXponential enrichment). We recently found t...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5009754/ https://ncbi.nlm.nih.gov/pubmed/27387284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw619 |
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