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Post-ExSELEX stabilization of an unnatural-base DNA aptamer targeting VEGF(165) toward pharmaceutical applications

A new technology, genetic alphabet expansion using artificial bases (unnatural bases), has created high-affinity DNA ligands (aptamers) that specifically bind to target proteins by ExSELEX (genetic alphabet Expansion for Systematic Evolution of Ligands by EXponential enrichment). We recently found t...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Kimoto, Michiko, Nakamura, Mana, Hirao, Ichiro
格式: Artigo
語言:Inglês
出版: Oxford University Press 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009754/
https://ncbi.nlm.nih.gov/pubmed/27387284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw619
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