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Selection of DNA Aptamers for Ovarian Cancer Biomarker CA125 Using One-Pot SELEX and High-Throughput Sequencing

CA125 is a mucin glycoprotein whose concentration in serum correlates with a woman's risk of developing ovarian cancer and also indicates response to therapy in diagnosed patients. Accurate detection of this large, complex protein in patient samples is of great clinical relevance. We suggest th...

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Detalhes bibliográficos
Publicado no:J Nucleic Acids
Main Authors: Scoville, Delia J., Uhm, Tae Kyu Brian, Shallcross, Jamie A., Whelan, Rebecca J.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322571/
https://ncbi.nlm.nih.gov/pubmed/28280637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9879135
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