Selection of DNA Aptamers for Ovarian Cancer Biomarker CA125 Using One-Pot SELEX and High-Throughput Sequencing

CA125 is a mucin glycoprotein whose concentration in serum correlates with a woman's risk of developing ovarian cancer and also indicates response to therapy in diagnosed patients. Accurate detection of this large, complex protein in patient samples is of great clinical relevance. We suggest th...

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Dades bibliogràfiques
Publicat a:J Nucleic Acids
Autors principals: Scoville, Delia J., Uhm, Tae Kyu Brian, Shallcross, Jamie A., Whelan, Rebecca J.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322571/
https://ncbi.nlm.nih.gov/pubmed/28280637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9879135
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