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Characterisation of aptamer–target interactions by branched selection and high-throughput sequencing of SELEX pools

Nucleic acid aptamer selection by systematic evolution of ligands by exponential enrichment (SELEX) has shown great promise for use in the development of research tools, therapeutics and diagnostics. Typically, aptamers are identified from libraries containing up to 10(16) different RNA or DNA seque...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Dupont, Daniel M., Larsen, Niels, Jensen, Jan. K., Andreasen, Peter A., Kjems, Jørgen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666376/
https://ncbi.nlm.nih.gov/pubmed/26163061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv700
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