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Characterisation of aptamer–target interactions by branched selection and high-throughput sequencing of SELEX pools

Nucleic acid aptamer selection by systematic evolution of ligands by exponential enrichment (SELEX) has shown great promise for use in the development of research tools, therapeutics and diagnostics. Typically, aptamers are identified from libraries containing up to 10(16) different RNA or DNA seque...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Dupont, Daniel M., Larsen, Niels, Jensen, Jan. K., Andreasen, Peter A., Kjems, Jørgen
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666376/
https://ncbi.nlm.nih.gov/pubmed/26163061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv700
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