Characterisation of aptamer–target interactions by branched selection and high-throughput sequencing of SELEX pools

Nucleic acid aptamer selection by systematic evolution of ligands by exponential enrichment (SELEX) has shown great promise for use in the development of research tools, therapeutics and diagnostics. Typically, aptamers are identified from libraries containing up to 10(16) different RNA or DNA seque...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Dupont, Daniel M., Larsen, Niels, Jensen, Jan. K., Andreasen, Peter A., Kjems, Jørgen
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Methods Online
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666376/
https://ncbi.nlm.nih.gov/pubmed/26163061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv700
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