Identification of nucleic acid aptamers against lactate dehydrogenase via SELEX and high-throughput sequencing

Nucleic acid aptamers are small fragments of DNA or RNA molecules binding specifically to targets, which can be obtained through in vitro screening via systematic evolution of ligands by exponential enrichment (SELEX). Lactate dehydrogenase (LDH) is an important tumor marker, whose level in patients...

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Detalles Bibliográficos
Publicado en:Anal Bioanal Chem
Main Authors: Guo, Linghui, Song, Ying, Yuan, Yanwen, Chen, Jinlei, Liang, Haifeng, Guo, Fei, Yu, Zhi, Liang, Pei, Wang, Yapei, Wang, Pu
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2021
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141549/
https://ncbi.nlm.nih.gov/pubmed/34028561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-021-03397-2
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