Hybrid-Type SELEX for the Selection of Artificial Nucleic Acid Aptamers Exhibiting Cell Internalization Activity

Nucleic acid aptamers have attracted considerable attention as next-generation pharmaceutical agents and delivery vehicles for small molecule drugs and therapeutic oligonucleotides. Chemical modification is an effective approach for improving the functionality of aptamers. However, the process of se...

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Vydáno v:Pharmaceutics
Hlavní autoři: Uemachi, Hiro, Kasahara, Yuuya, Tanaka, Keisuke, Okuda, Takumi, Yoneda, Yoshihiro, Obika, Satoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8232673/
https://ncbi.nlm.nih.gov/pubmed/34204006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13060888
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