Study on Suitability of KOD DNA Polymerase for Enzymatic Production of Artificial Nucleic Acids Using Base/Sugar Modified Nucleoside Triphosphates

Recently, KOD and its related DNA polymerases have been used for preparing various modified nucleic acids, including not only base-modified nucleic acids, but also sugar-modified ones, such as bridged/locked nucleic acid (BNA/LNA) which would be promising candidates for nucleic acid drugs. However,...

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Bibliographic Details
Published in:Molecules
Main Authors: Kuwahara, Masayasu, Takano, Yuuki, Kasahara, Yuuya, Nara, Hiroki, Ozaki, Hiroaki, Sawai, Hiroaki, Sugiyama, Akio, Obika, Satoshi
Format: Artigo
Language:Inglês
Published: MDPI 2010
Subjects:
Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259326/
https://ncbi.nlm.nih.gov/pubmed/21076389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15118229
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