Systematic analysis of enzymatic DNA polymerization using oligo-DNA templates and triphosphate analogs involving 2′,4′-bridged nucleosides

In order to systematically analyze the effects of nucleoside modification of sugar moieties in DNA polymerase reactions, we synthesized 16 modified templates containing 2′,4′-bridged nucleotides and three types of 2′,4′-bridged nucleoside-5′-triphospates with different bridging structures. Among the...

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Detalhes bibliográficos
Main Authors: Kuwahara, Masayasu, Obika, Satoshi, Nagashima, Jun-ichi, Ohta, Yuki, Suto, Yoshiyuki, Ozaki, Hiroaki, Sawai, Hiroaki, Imanishi, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Chemistry and Synthetic Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490744/
https://ncbi.nlm.nih.gov/pubmed/18583360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn404
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