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An allylic/acyclic adenosine nucleoside triphosphate for termination of DNA synthesis by DNA template-dependent polymerases.

An allylic adenosine triphosphate analog (AATP) was tested as a substrate for commercially available DNA polymerases. All but one of the enzymes assayed incorporated AATP opposite thymidine (T) with concomitant termination of the elongation reaction. A concentration of only 1 microM was sufficient f...

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Detaylı Bibliyografya
Asıl Yazarlar: Martinez, C I, Thoresen, L H, Gibbs, R A, Burgess, K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC148311/
https://ncbi.nlm.nih.gov/pubmed/9973613
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