An allylic/acyclic adenosine nucleoside triphosphate for termination of DNA synthesis by DNA template-dependent polymerases.

An allylic adenosine triphosphate analog (AATP) was tested as a substrate for commercially available DNA polymerases. All but one of the enzymes assayed incorporated AATP opposite thymidine (T) with concomitant termination of the elongation reaction. A concentration of only 1 microM was sufficient f...

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Bibliographic Details

Published in:	Nucleic Acids Res
Main Authors:	Martinez, C I, Thoresen, L H, Gibbs, R A, Burgess, K
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 1999
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148311/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9973613/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.5.1271
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