An allylic/acyclic adenosine nucleoside triphosphate for termination of DNA synthesis by DNA template-dependent polymerases.

An allylic adenosine triphosphate analog (AATP) was tested as a substrate for commercially available DNA polymerases. All but one of the enzymes assayed incorporated AATP opposite thymidine (T) with concomitant termination of the elongation reaction. A concentration of only 1 microM was sufficient f...

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Bibliografiska uppgifter

I publikationen:	Nucleic Acids Res
Huvudupphov:	Martinez, C I, Thoresen, L H, Gibbs, R A, Burgess, K
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Oxford University Press 1999
Ämnen:	Research Article
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148311/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9973613/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.5.1271
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