Enzymatic Primer-Extension with Glycerol-Nucleoside Triphosphates on DNA Templates

BACKGROUND: Glycerol nucleic acid (GNA) has an acyclic phosphoglycerol backbone repeat-unit, but forms stable duplexes based on Watson-Crick base-pairing. Because of its structural simplicity, GNA is of particular interest with respect to the possibility of evolving functional polymers by in vitro s...

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Detalhes bibliográficos
Main Authors: Chen, Jesse J., Tsai, Ching-Hsuan, Cai, Xin, Horhota, Allen T., McLaughlin, Larry W., Szostak, Jack W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654545/
https://ncbi.nlm.nih.gov/pubmed/19305495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004949
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