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Template-Directed Catalysis of a Multistep Reaction Pathway for Nonenzymatic RNA Primer Extension

[Image: see text] Before the advent of polymerase enzymes, the copying of genetic material during the origin of life may have involved the nonenzymatic polymerization of RNA monomers that are more reactive than the biological nucleoside triphosphates. Activated RNA monomers such as nucleotide 5′-pho...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochemistry
Prif Awduron: Walton, Travis, Pazienza, Lydia, Szostak, Jack W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2018
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547881/
https://ncbi.nlm.nih.gov/pubmed/30566332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01156
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