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Crystallographic observation of nonenzymatic RNA primer extension

The importance of genome replication has inspired detailed crystallographic studies of enzymatic DNA/RNA polymerization. In contrast, the mechanism of nonenzymatic polymerization is less well understood, despite its critical role in the origin of life. Here we report the direct observation of nonenz...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Zhang, Wen, Walton, Travis, Li, Li, Szostak, Jack W
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980232/
https://ncbi.nlm.nih.gov/pubmed/29851379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36422
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