Non-enzymatic primer extension with strand displacement

Non-enzymatic RNA self-replication is integral to the emergence of the ‘RNA World’. Despite considerable progress in non-enzymatic template copying, demonstrating a full replication cycle remains challenging due to the difficulty of separating the strands of the product duplex. Here, we report a pre...

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Vydáno v:eLife
Hlavní autoři: Zhou, Lijun, Kim, Seohyun Chris, Ho, Katherine H, O'Flaherty, Derek K, Giurgiu, Constantin, Wright, Tom H, Szostak, Jack W
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
Biochemistry and Chemical Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872209/
https://ncbi.nlm.nih.gov/pubmed/31702557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51888
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