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Template‐Directed Copying of RNA by Non‐enzymatic Ligation

The non‐enzymatic replication of the primordial genetic material is thought to have enabled the evolution of early forms of RNA‐based life. However, the replication of oligonucleotides long enough to encode catalytic functions is problematic due to the low efficiency of template copying with mononuc...

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Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Zhou, Lijun, O'Flaherty, Derek K., Szostak, Jack W.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496532/
https://ncbi.nlm.nih.gov/pubmed/32558121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202004934
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