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Template‐Directed Copying of RNA by Non‐enzymatic Ligation

The non‐enzymatic replication of the primordial genetic material is thought to have enabled the evolution of early forms of RNA‐based life. However, the replication of oligonucleotides long enough to encode catalytic functions is problematic due to the low efficiency of template copying with mononuc...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Zhou, Lijun, O'Flaherty, Derek K., Szostak, Jack W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496532/
https://ncbi.nlm.nih.gov/pubmed/32558121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202004934
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