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A Mechanistic Explanation for the Regioselectivity of Nonenzymatic RNA Primer Extension
[Image: see text] A working model of nonenzymatic RNA primer extension could illuminate how prebiotic chemistry transitioned to biology. All currently known experimental reconstructions of nonenzymatic RNA primer extension yield a mixture of 2′-5′ and 3′-5′ internucleotide linkages. Although long se...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2017
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6326530/ https://ncbi.nlm.nih.gov/pubmed/29112424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b08784 |
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