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Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide
[Image: see text] Nonenzymatic RNA primer extension by activated mononucleotides has long served as a model for the study of prebiotic RNA copying. We have recently shown that the rate of primer extension is greatly enhanced by the formation of an imidazolium-bridged dinucleotide between the incomin...
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| Vydáno v: | J Am Chem Soc |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Chemical
Society
2018
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6326529/ https://ncbi.nlm.nih.gov/pubmed/29411978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11750 |
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