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Prebiotically Plausible “Patching” of RNA Backbone Cleavage through a 3′–5′ Pyrophosphate Linkage
[Image: see text] Achieving multiple cycles of RNA replication within a model protocell would be a critical step toward demonstrating a path from prebiotic chemistry to cellular biology. Any model for early life based on an “RNA world” must account for RNA strand cleavage and hydrolysis, which would...
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| Pubblicato in: | J Am Chem Soc |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2019
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7577263/ https://ncbi.nlm.nih.gov/pubmed/31651170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b08237 |
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