Prebiotically Plausible “Patching” of RNA Backbone Cleavage through a 3′–5′ Pyrophosphate Linkage

[Image: see text] Achieving multiple cycles of RNA replication within a model protocell would be a critical step toward demonstrating a path from prebiotic chemistry to cellular biology. Any model for early life based on an “RNA world” must account for RNA strand cleavage and hydrolysis, which would...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Wright, Tom H., Giurgiu, Constantin, Zhang, Wen, Radakovic, Aleksandar, O’Flaherty, Derek K., Zhou, Lijun, Szostak, Jack W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2019
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577263/
https://ncbi.nlm.nih.gov/pubmed/31651170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b08237
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge