Identification of nucleic acid aptamers against lactate dehydrogenase via SELEX and high-throughput sequencing

Nucleic acid aptamers are small fragments of DNA or RNA molecules binding specifically to targets, which can be obtained through in vitro screening via systematic evolution of ligands by exponential enrichment (SELEX). Lactate dehydrogenase (LDH) is an important tumor marker, whose level in patients...

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Publicat a:Anal Bioanal Chem
Autors principals: Guo, Linghui, Song, Ying, Yuan, Yanwen, Chen, Jinlei, Liang, Haifeng, Guo, Fei, Yu, Zhi, Liang, Pei, Wang, Yapei, Wang, Pu
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2021
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141549/
https://ncbi.nlm.nih.gov/pubmed/34028561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-021-03397-2
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