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Selection of DNA aptamers for ovarian cancer biomarker HE4 using CE-SELEX and high-throughput sequencing

The development of novel affinity probes for cancer biomarkers may enable powerful improvements in analytical methods for detecting and treating cancer. In this report, we describe our use of capillary electrophoresis (CE) as the separation mechanism in the process of selecting DNA aptamers with aff...

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Bibliografski detalji
Izdano u:Anal Bioanal Chem
Glavni autori: Eaton, Rachel M., Shallcross, Jamie A., Mael, Liora E., Mears, Kepler S., Minkoff, Lisa, Scoville, Delia J., Whelan, Rebecca J.
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551533/
https://ncbi.nlm.nih.gov/pubmed/25863801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-015-8665-7
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