Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques

Despite successful control of viremia, many HIV-infected individuals given antiretroviral therapy (ART) exhibit residual inflammation, which is associated with non–AIDS-related morbidity and mortality and may contribute to virus persistence during ART. Here, we investigated the effects of IL-21 admi...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Micci, Luca, Ryan, Emily S., Fromentin, Rémi, Bosinger, Steven E., Harper, Justin L., He, Tianyu, Paganini, Sara, Easley, Kirk A., Chahroudi, Ann, Benne, Clarisse, Gumber, Sanjeev, McGary, Colleen S., Rogers, Kenneth A., Deleage, Claire, Lucero, Carissa, Byrareddy, Siddappa N., Apetrei, Cristian, Estes, Jacob D., Lifson, Jeffrey D., Piatak, Michael, Chomont, Nicolas, Villinger, Francois, Silvestri, Guido, Brenchley, Jason M., Paiardini, Mirko
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665780/
https://ncbi.nlm.nih.gov/pubmed/26551680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81400
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