Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques

Despite successful control of viremia, many HIV-infected individuals given antiretroviral therapy (ART) exhibit residual inflammation, which is associated with non–AIDS-related morbidity and mortality and may contribute to virus persistence during ART. Here, we investigated the effects of IL-21 admi...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Micci, Luca, Ryan, Emily S., Fromentin, Rémi, Bosinger, Steven E., Harper, Justin L., He, Tianyu, Paganini, Sara, Easley, Kirk A., Chahroudi, Ann, Benne, Clarisse, Gumber, Sanjeev, McGary, Colleen S., Rogers, Kenneth A., Deleage, Claire, Lucero, Carissa, Byrareddy, Siddappa N., Apetrei, Cristian, Estes, Jacob D., Lifson, Jeffrey D., Piatak, Michael, Chomont, Nicolas, Villinger, Francois, Silvestri, Guido, Brenchley, Jason M., Paiardini, Mirko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665780/
https://ncbi.nlm.nih.gov/pubmed/26551680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81400
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