Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques

Despite successful control of viremia, many HIV-infected individuals given antiretroviral therapy (ART) exhibit residual inflammation, which is associated with non–AIDS-related morbidity and mortality and may contribute to virus persistence during ART. Here, we investigated the effects of IL-21 admi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Clin Invest
Κύριοι συγγραφείς: Micci, Luca, Ryan, Emily S., Fromentin, Rémi, Bosinger, Steven E., Harper, Justin L., He, Tianyu, Paganini, Sara, Easley, Kirk A., Chahroudi, Ann, Benne, Clarisse, Gumber, Sanjeev, McGary, Colleen S., Rogers, Kenneth A., Deleage, Claire, Lucero, Carissa, Byrareddy, Siddappa N., Apetrei, Cristian, Estes, Jacob D., Lifson, Jeffrey D., Piatak, Michael, Chomont, Nicolas, Villinger, Francois, Silvestri, Guido, Brenchley, Jason M., Paiardini, Mirko
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2015
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665780/
https://ncbi.nlm.nih.gov/pubmed/26551680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81400
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