Increased Stability and Limited Proliferation of CD4(+) Central Memory T Cells Differentiate Nonprogressive Simian Immunodeficiency Virus (SIV) Infection of Sooty Mangabeys from Progressive SIV Infection of Rhesus Macaques

Depletion of CD4(+) central memory T (TCM) cells dictates the tempo of progression to AIDS in simian immunodeficiency virus (SIV)-infected rhesus macaques (RMs) both in the natural history of infection and in the context of vaccination. CD4(+) TCM cells of sooty mangabeys (SMs), a natural host for S...

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Detalhes bibliográficos
Main Authors: McGary, Colleen S., Cervasi, Barbara, Chahroudi, Ann, Micci, Luca, Taaffe, Jessica, Meeker, Tracy, Silvestri, Guido, Davenport, Miles P., Paiardini, Mirko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993768/
https://ncbi.nlm.nih.gov/pubmed/24501416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03515-13
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