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Discovery and functional characterization of diverse Class 2 CRISPR-Cas systems
Microbial CRISPR-Cas systems are divided into Class 1, with multisubunit effector complexes, and Class 2, with single protein effectors. Currently, only two Class 2 effectors, Cas9 and Cpf1, are known. We describe here three distinct Class 2 CRISPR-Cas systems. The effectors of two of the identified...
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| 發表在: | Mol Cell |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4660269/ https://ncbi.nlm.nih.gov/pubmed/26593719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.10.008 |
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