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RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development.

We describe a system to evaluate the function of lymphocyte-specific and generally expressed genes in the differentiation and/or function of lymphocytes. RAG-2 (recombination-activating gene 2)-deficient mice have no mature B and T lymphocytes due to the inability to initiate VDJ recombination. Blas...

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Sonraí Bibleagrafaíochta
Main Authors: Chen, J, Lansford, R, Stewart, V, Young, F, Alt, F W
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1993
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC46545/
https://ncbi.nlm.nih.gov/pubmed/8506294
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