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Molecular basis of a multiple lymphokine deficiency in a patient with severe combined immunodeficiency.

We have previously reported that the T lymphocytes of a child with severe combined immunodeficiency are defective in the transcription of several lymphokine genes that include IL2, IL3, IL4, and IL5, which encode interleukins 2, 3, 4, and 5 (IL-2, -3, -4, and -5). To determine whether the defect in...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Castigli, E, Pahwa, R, Good, R A, Geha, R S, Chatila, T A
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1993
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46586/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8506326/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4728
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