Induction of alloantigen-specific tolerance by B cells from CD40-deficient mice.

Interaction between CD40 on B cells and CD40 ligand molecules on T cells is pivotal for the generation of a thymus-dependent antibody response. Here we show that B cells deficient in CD40 expression are unable to elicit the proliferation of allogeneic T cells in vitro. More importantly, mice immuniz...

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Main Authors: Holländer, G A, Castigli, E, Kulbacki, R, Su, M, Burakoff, S J, Gutierrez-Ramos, J C, Geha, R S
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC39394/
https://ncbi.nlm.nih.gov/pubmed/8643517
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