Induction of alloantigen-specific tolerance by B cells from CD40-deficient mice.
Interaction between CD40 on B cells and CD40 ligand molecules on T cells is pivotal for the generation of a thymus-dependent antibody response. Here we show that B cells deficient in CD40 expression are unable to elicit the proliferation of allogeneic T cells in vitro. More importantly, mice immuniz...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1996
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39394/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643517/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.10.4994 |
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