RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development.
We describe a system to evaluate the function of lymphocyte-specific and generally expressed genes in the differentiation and/or function of lymphocytes. RAG-2 (recombination-activating gene 2)-deficient mice have no mature B and T lymphocytes due to the inability to initiate VDJ recombination. Blas...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1993
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46545/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8506294/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4528 |
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